NURS 364 Lecture Notes - Lecture 18: Distal Convoluted Tubule, Peritubular Capillaries, Renal Artery

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Review of structure and function of the renal and urologic systems. Functional unit of the kidney (1. 2 million nephrons/kidney) Receive 1000 to 1200 ml of blood per minute. Depends upon the amount of pressure on the juxtaglomerular cells that sit alongside the glomerulus. Decreased pressure leads to increased renin secretion. Effect of renal blood flow on gfr. Increased renal blood flow reduce tendency of glomerular cop to resist filtration through glomerulus increased gfr. Sympathetic stimulation preferential afferent arteriolar constriction decrease renal blood flow & decrease hydrostatic pressure glomerular pressure decreased gfr. Decreased bp automatic afferent arteriolar constriction decrease renal blood flow decreased gfr less water loss increase blood volume systemic bp. Movement of protein free plasma across the glomerular membrane (hydrostatic pressure) Movement of fluid/solutes from tubular lumen to the peritubular capillaries. Transfer of substances from the peritubular capillaries to the tubular lumen. Elimination of fluids/substances in the final urine.

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