Biology And Biomedical Sciences BIOL 2960 Lecture Notes - Lecture 20: Prokaryote, Dna Polymerase Iii Holoenzyme, Okazaki Fragments
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Study guide 8: nucleic acid structure and replication (lectures 17-20) At the end of this unit, you should be able to define and/or use the following terms: Replication: replication mechanism: cell cycle s phase; Semiconservative replication; replication fork, leading strand, lagging strand, Okazaki fragment, rna primer, 3"oh of deoxyribose, phosphodiester bond, deoxynucleotide triphosphate (dntp), 5" 3" directionality of synthesis: replication enzymes and reactions: dna. Polymerase i, dna polymerase iii (dimer, complexed with other proteins), primase, Ligase, single stranded dna binding protein (ssbp), condensation reaction, 5" 3" exonuclease activity, processivity, error rate, fidelity, replisome: replication initiation: origin of replication (oric), dnaa, dnaa binding sites, replication bubble, bidirectional replication, Dna topoisomerase, supercoiling, multiple origins of replication: replication termination: terminus region (ter), telomeres, telomere repeats, end replication problem for linear chromosomes, telomerase enzymes, telomeric cap, telomerase activity and cancer cells. When you"re done studying for this unit, you should be able to: diagram a general structure of the hereditary material, dna.