BIOL 321 Lecture Notes - Lecture 7: Egg Cell, Meristics, Genome-Wide Association Study
Document Summary
Types of complex traits: complex traits can differ in expresion: countable (meristic) can take on integer values only. Crop yields, height, etc. threshold trait: has an underlying quantitative distribution, but the trait only appears only if a threshold is crossed. Multifactorial traits - recurrence risk: the recurrence risk for an abnormal phenotype depends upon: Related parents have a higher risk of having a child with a complex disorder. Parents with two affected children have a greater risk of having another affected child, since their genotypes are likely close to the threshold. A severe phenotype indicates the genotype is well over the threshold, and increases the risk of having another affected child. For complex traits expressed more frequently in one sex, the less frequently affected sex has a. Heritability values: heritability = 1. 0 lower recurrence risk. Genetic factors contribute 100% to phenotypic variation. Environmental factors have little to no effect on phenotypic variation: heritability = 0. 0.