BIOLOGY 253 Lecture Notes - Lecture 8: Nicotiana Rustica, Lung Cancer, American Tobacco Company

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Cancer is caused by mutations in specific genes. Causes of cancer: cancer risk in populations correlates mainly with environmental factors, economics, and diet. Understand how smoking causes lung and sun exposure cause cancer. Improtant concepts and skills include: dna, mutation, carcinogen, gene expression (transcription), dna replication, cell cycle, cell signaling, apoptosis, and interpretation of data in a graph. Since everyone took bio 141 and 142, you hopefully understand that the dna in the nucleus of each cell controls the functions of most of the cells of your body. If the dna encodes the correct proteinall is well. A mistake in the dna sequence is called a mutation. Suppose the correct dna sequence in a part of the k-ras gene is: ggagctggtg A mutation of that sequence could be: ggagcttgtg Other times they yield a protein that functions slightly differently but does not cause disease.

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