NUTR SCI 132 Lecture Notes - Lecture 2: Natural Experiment, Animal Testing, Blind Experiment

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Anecdotal evidence - based on what you heard. Scientific method (to go around this) - ask a question, is there something here with all these anecdotes. Control group- no treatment: groups otherwise identical. Case study - based on anecdote (suggests direction for research) Epidemiological study - (observation) natural experiment conducted by a population on itself. Places with more breast cancer & fat (us & finland) extremely industrialized. African places with less of both = less industrialized. Other confounders: physical activity, less detection/medical care, pollution, Case control study different genetics, different diets: match cases with control (match hospitalized breast cancer with someone else without it) Intervention studies: animal study, experimental group - gets treatment, control group - no treatment, compare outcomes (did they get less cancer, less heart disease, etc. ) Human clinical trial: experimental group - gets treatment, control group - no treatment, compare outcomes at end of study. Humans more complicated to study than animals - consideration in human trials:

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