BIOL 2100 Lecture Notes - Lecture 36: Intron, Guanine, Peptide
Document Summary
Progeria = rapid aging resulting in a problem with transcription/translation. Only some genes are being expressed at any given moment. Gene expression requires transcription of the gene. Both replication and transcription synthesize nucleic acids. Transcription = synthesis of rna using dna as a template. Only certain regions are used as templates. One of the two strands is the template. A promoter starts the process of transcription. Sequence of dna that recruits rna polymerase. Dictates where rna polymerase binds to the strand, and sets the orientation to show which strand is the template strand. Sigma = protein that binds to the promoter. Transcription factors = proteins that bind to the dna that serve as recruiters for rna polymerase. Along the length of the dna, genes can use either strand for transcription. 3" cagtctatcagttac 5" - non-template (coding strand) Rna polymerase reads the strand from 3" to 5" but codes from 5" to 3". Prokaryotes have a sequence that acts a terminator.