BIOL 3600 Lecture Notes - Lecture 23: Cori Cycle, Acetyl-Coa, Oxidative Phosphorylation
Document Summary
In the fed-state, the insulin hormone dominates, upregulating glucose uptake, glycogenesis, and lipogenesis. In diabetes mellitus, there is no insulin signal (type i) or it is ineffective (type ii) so the glucagon signal dominates, leading to ketosis or even ketoacidosis. #2 metabolic pathways need to be regulated at the organismal level and are interdependent (such as in the cori cycle). Interdependent = between cells, not just within cells. Organismal level = responds to needs of the organism. Salmon colored arrow pathway glycolysis is very important pathway because glucose is the preferred nutrient fuel of most cells, and the brain, and has been highlighted in the Green jellybeans (dark green: nadh & light green: fadh2) and yellow jellybeans (atp) Blue circle is cac and how much high energy electrons come off all feed into the beta sheet (magenta and purple arrows going in opposite direction). Magenta is etc and purple is coupled to it so it is oxidative phosphorylation of the