BIOL 3600 Lecture Notes - Lecture 14: Malate-Aspartate Shuttle, Oxidative Phosphorylation, Coenzyme Q10
25 Apr 2020
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Document Summary
The biochemical role of the citric acid cycle is the generation of high-energy electrons. It takes place in the mitochondrial matrix as does oxidative phosphorylation, which converts the high-energy electrons into atp. #2 the electron transport chain (etc) and oxidative phosphorylation (op) take place within the inner mitochondrial membrane. The location that we introduced is ch 17 is now even more important. Take place on a surface within a membrane. Defined these 3 spaces: cytoplasm on outside, intermembrane space (effectively the cytoplasm), and then the matrix (yellow) aqueous environment where pyruvate oxidation and the citric acid cycle take. Processes of ch 18 take place within the magenta membrane. What crosses into the mitochondrin is pyruvate (the product of glycolysis) crosses as fuel into the membrane. Molecular oxygen (o2) isn"t polar and gets across the membrane. Majority of atp is made on the matrix side of the inner membrane and then is transported out.
