BIOL 118 Lecture Notes - Lecture 27: Normal Route, Variolation, Lady Mary Wortley Montagu

• School: University of San Diego
• Department: Biology Courses
• Course: BIOL 118
• Professor: Terry Bird

Document Summary

Clinical aspects of small pox (possible exam q) **** Allowed extermination of virus & using vaccine. Target for eradication (only target humans & only humans) Contributed to virus being spread over vast distances. Can infect a lot of diff types of tissues. Allowed invasion of empires (inca & aztec) It was already pre-invaded with small pox fr mexico. Higher mortality rate for those in the new world. Offensive disease that allowed europeans to conquer. Variolation*** (using live virus to induce immunity--diff fr vaccination) Taking fluid/scabs of blisters & rubbing it onto skin of ppl who havent been exposed before. Recognized that ppl got smallpox but a mild version & they survived. Similar process practiced in china before too + arabs & turks. How did variolation provide immunity to smallpox. Targeting/exposing to tissue less crucial to survivability. Takes longer via skin: more time for the immune system to respond. Risk of variolation was better than going normal route.