BIOL 118 Lecture Notes - Lecture 29: Extracellular Polymeric Substance, Quorum Sensing, Small Intestine
Document Summary
Every outbreak can be traced back to here. Floods contaminates wells & drinking water. Most epidemics localized to third world countries to due sanitation and/or infrastructure issues. Innate system: rapid change in ph levels blocks collera. To be infected has to injest 10^6 to 10^11 bacteria. If it can get through the stomach it can survive the ph of the small intestine. Its so quick, 24 hrs to lose 20 liters of h20. Small intestine micro villi important to v. cholerae. Toxins causes release of huge amounts of water via causing diarrhea. High density population of bacteria living attached to solid surface. Large number: begins to secrete compounds: exopolysaccharides (similar to slime capsule) Long strands of sugar making it outside the cell matrix. Makes huge amts so large populations can live inside it. Allows it to stay attached in an environmnent when there are large currents. Has pores that allows water to flow through.