BIOL 118 Lecture Notes - Lecture 26: Smallpox, Malignancy, 2 On

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Makes blisters filled with fluids that are filled with viruses. 4 variations that can occur after infection. Ordinary (30% mortality rate-for euro pops-pops that have evolved) Vaccine modified (2%, previously vaccinated, not lethal) Malignant pox (6. 7% of cases, 96% mortality, large flat lesions as result of tissue damage) Hemorrhagic (2. 4% cases, 96% mortality, bleeds below the skin, may be no rash) Once immune to one immune to all, except vaccine modified. If cornea infected, accounted for blindess in 18th cent europe. For every patient infected, patient zero can cause infection of 5-10 ppl. High bc virus is small and can exist via droplets o saliver (coughing, breathing) Virus can remain viable (not alive) for months even in dry. Didn"t have to be in person, allowed it to live on goods, ie living on bales of cotton bc it didn"t need host, no association with live person like yp. Household servants who had survived smallpox were highly sought.

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