BIOL 118 Lecture Notes - Lecture 25: Zoonosis, Poxviridae, Smallpox

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Can"t be treated by antibiotics; no active metabolism. Antibiotics kill by disrupting antibiotics of bacteria. Belongs to fam of closely related viruses (poxviridae) Diverged bc became adapted to diff types of organisms * Where it can jump back in forth not true for small pox. Most similar w/ virus that infects camels & gerbils. Diff fr others: spiked proteins (important for when it comes time to be infectiorus) Interior w/ dna genome bringing in own special enzymes. Epidemic throughout africa & asia & europe. Gods related to small pox statred to appear. May suggest that greater resistant was acquired and/or attenuated overtime. Danish ship brought smallpox to iceland in 1241 killing 40% of pop (20k) Isolated bc no immunity/less evolution > less resistance. Small pox larger than all the other plagues put together*** By 20th cent more than 300mil ppl killed. Most likely infected cells of the mouth & upper respiratory tract.

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