BME 410 Lecture Notes - Lecture 1: Tissue Engineering, Cilium, Nuclear Lamina

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20 Apr 2016
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Regenerative medicine: must learn how to regenerate organs/cells from the patient because patients too often reject them. Immunosuppressant drugs currently need to be used: number of people on waitlist has long exceeded transplants and donors. Drug screening: existing model systems do not resemble human tissue for drug screening. Genotype: is the genetic makeup of a person. Phenotype: is the physical manifestation of an inherited trait or disease. Tissue engineered skin: contains the same layers however missing a variety of cells such as langerhorns, endothelial, red blood cell etc. Organs on chips: device that mimics function of a living lung: membrane: lung cells on top, capillary cells on bottom of porous membrane, vacuum channels: stretch and relax rhythmically (cid:1) (cid:1)

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