BISC 220Lg Lecture Notes - Lecture 6: Addison-Wesley, Nuclear Pore, Secretion

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The messenger rna leaves the nucleus thru a nuclear pore and then interacts with ribosomes in the cytoplasm. Some of these ribosomes are free and the proteins synthesized by these end up being free proteins. Many ribosomes are attached to the endoplasmic reticulum. In order to form mature proteins, extra processing must take place: the nucleus, cisternal space and lumen mean the same thing. *pay attention to the nuclear envelope in this diagram. It is made up of these series of sac-like structures. You can see the eight sub-units of the nuclear pore. *many regulatory proteins are formed in the cytoplasm. The outer membrane extends out and forms part of the endoplasmic reticulum. The endoplasmic reticulum is made up of cisternae which is latin for sac. So there is a definite direction or polarity to the structure. i. ii. iii. There is a definite direction with the golgi apparatus.

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