NURS 3518 Lecture Notes - Lecture 6: Respiratory Tract, Adaptive Immune System, Endothelium
Document Summary
Chapter 6 innate immunity and inflammation study guide. Innate barriers natural barriers (epithelial cells, bacterial toxins, skin and mucous membranes, low ph of skin and stomach) Inflammation def. a programed response to cellular or tissue damage: designed to limit the extent of tissue damage, destroy the contaminating infectious organism, initiate the adaptive immune response, and begin the healing process. List the local changes in the process of inflammation: dilation of the blood vessels and increased blood flow, leading to erythema and warmth. Chemical components and mediators of inflammation p 141-147. What enzyme is necessary to arachidonic acid to form: explain the role of nitric oxide and prostacyclin. List local manifestations of inflammation: swelling, pain, heat, redness (erythema, exudate- results from increased vascular permeability and varies in composition, early and mild inflammation has serous exudate (watery, severe and advanced inflammation has fibrinous exudate (thick and clotted) If large numbers of leukocytes accumulate, is purulent suppurative exudate.