BIOC 3110 Lecture Notes - Lecture 38: Rna Splicing, Rna Polymerase Ii, Ribonuclease Iii

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Each rna type has a different type of processing. What classes of rna-protein complexes contribute to the maturation of rnas in eukaryotic cells: rrna processing- Begins as large 45s pre-rrna, which has to be matured into the three subspecies of rrna (18s, 5. 8s, ad 28s) Methylation occurs at ribose (cid:884)" ohs by snornps three mature rrnas. Once it is modified, rnase iii cleaves the strand to make the. This occurs in prokaryotes and eukaryotes: trna processing- 5" leader sequence end is removed by rnase p endonuclease (protein rna complex where the rna portion of protein is the catalytic site) (cid:885)" end is trimmed by another endonuclease cleavage. A (cid:498)cca is added at the (cid:885)" which allows all trnas to be charged with an amino acid in the translation process- by trna nucleotidyltransferase finally, sometimes base modifications occur that are used in translation machinery. This occurs in prokaryotes and eukaryotes: mrna processing-

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