BIOC 3110 Lecture Notes - Lecture 33: Phosphodiester Bond, Hydrogen Bond, Thymine

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Structures of bases: dna is polymer of 4 monomers, they are connected through phosphodiester bonds, on sugar, monomer made of base, sugar, and phosphate (cid:523)at (cid:885)" spot(cid:524) (cid:883)" spot is where the base attaches-either purine or pyrimidine. (cid:885)" spot with hydroxyl for the phosphodiester bond: )t goes from 5" end with the free phosphate (cid:885)" end with the free hydroxyl. 20% of nucleotides are cytosine, so you know 20% guanine, therefore 30% adenine and 30% thymine: the bases have the ability to hydrogen bond with each other, and then the hydrophobic interactions occur through base stacking (van de. Dna and rna have common and unique features. Dna has 4 monomers, made of base, sugar, and p. Rna has uracil base instead of thymine. Rna contains ribose (oh) sugar, instead of deoxyribose (h) at (cid:884)" spot, which leads to instability of rna strands. Rna is usually a single strand rather than two antiparallel. Dna and rna adopt multiple structures: dna-

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