ACB 8120 Lecture Notes - Lecture 78: Spina Bifida, Cranial Vault, Neural Tube

• School: University of Iowa
• Department: Anatomy and Cell Biology
• Course: ACB 8120
• Professor: Hoffman

Document Summary

Neural plate (ectoderm) becomes thicker in one area (neural plate) and starts to fold (due to notochord) and becomes the neural groove when the folds approach each other but do not touch. When they do touch, then it is called the neural tube (neuroectoderm). The ends of the neural tube are not closed and are called neuropores. The layer above is the surface ectoderm and will form the epidermis. Begins in the cervical area (middle) and spreads in the caudal and rostral directions. Associated with defects in overlying bony structures (cranial vault. Anencephaly : open brain and lack of a skull vault. Encephalocele : herniation of the brain and. Spina bifida occulta - failure of midline to fuse. Mild version closed spina bifida - vertebrae not fused, usually have hair growth above. Meningocele - meninges herniate into the cyst behind the spine, csf in the cyst. Meningomyelocele - meninges and spinal cord are in the cyst.