GCD 3022 Lecture Notes - Lecture 4: Chi-Squared Test, Punnett Square, Mendelian Inheritance

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(cid:800). (cid:799) mendel"s study of pea plants. Early ideas regarding inheritance included pangenesis and blending inheritance. By conducting single-factor crosses, mendel proposed three key ideas regarding inheritance. Genes are passed unaltered from generation to generation. The law of segregation states the following: the two copies of a gene segregate from each other during transmission from parent to offspring. A punnett square is used to deduce the outcome of single-factor crosses. By conducting two-factor crosses, mendel proposed the law of independent assortment: two different genes will randomly assort their alleles during the formation of haploid cells. Human inheritance patterns are determined by analyzing family trees known as pedigrees. According to the product rule, the probability of two or more independent outcomes is equal to the product of their individual probabilities. This rule can be used to predict the outcome of crosses involving two or more genes. The binomial expansion is used to predict the probability of an unordered combination of outcomes.

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