BIOL 4004 Lecture Notes - Lecture 3: Repressor, Histone Deacetylase, Transcriptional Regulation
Document Summary
Gene control overview (slide 3): which steps do you think are commonly operated: transcription: starts gene expression, translation and mrna degradation by small rnas: partially stops/reduces gene expression, protein degradation: completely stops gene expression. Eukaryotic transcription repression: competitive: the repressor and the activator share the same binding site. If the repressor beats the activator to the binding site, gene expression is inhibited. If the activator beats the repressor to the binding site, gene expression is activated: masking: the repressor and the activator bind at separate sites within close proximity of one another. The repressor binds to the activator, rendering it useless: direct: the repressor and the activator bind at separate sites. At the anterior, why is the eve gene not expressed even if hunchback and. Well it"s more complicated than that: look at the giant and kruppel genes (dashed line). When giant and kruppel are present, the eve gene is not expressed (no yellow strip).
