EHS 260 Lecture Notes - Lecture 28: Physical Activity Level, Landmark Point, Relative Risk
18 Jun 2018
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Department
Course
Professor
Nurses Health Study
The Nurses’ Health Study is among the largest and longest running investigations of factors that
influence women’s health.
Started in 1976 and expanded in 1989,
Information provided by the 238,000 dedicated nurse-participants has led to many new insights
on health and disease.
While the prevention of cancer is still a primary focus, the study has also produced landmark
data on cardiovascular disease, diabetes and many other conditions.
Hu et al., 2000
Physical activity level and walking activity (both measured in MET-h per week) in
relation to total stroke incidence.
Data are the average reports gathered on three occasions eight, six, and two years prior
to assessment of outcome and adjusted for age and other potentially confounding
factors.
The relationship is inverse, graded and statistically significant.
Although adjustment for potentially confounding factors somewhat attenuated the risk,
this remained significant.
Physical Fitness and CHD
Aerobics Center Longitudinal Study (ACLS)
•N=>25,000 men
•Test: maximal treadmill test
•Compared to men who were fit (quintile 2-5) those who were unfit (quintile 1) had 1.7 times the
relative risk of CVD
–Compared to men who did not smoke, smokers had 1.57 times the risk of CVD
–Compared to those with normal CHOL, those with high CHOL had 1.65 times the risk of
CVD
Rrelationship between physical activity/fitness and risk for CHD:
consistently reported and inverse;
find more resources at oneclass.com
find more resources at oneclass.com
Document Summary
The nurses" health study is among the largest and longest running investigations of factors that influence women"s health. Started in 1976 and expanded in 1989, Information provided by the 238,000 dedicated nurse-participants has led to many new insights on health and disease. While the prevention of cancer is still a primary focus, the study has also produced landmark data on cardiovascular disease, diabetes and many other conditions. Physical activity level and walking activity (both measured in met-h per week) in relation to total stroke incidence. Data are the average reports gathered on three occasions eight, six, and two years prior to assessment of outcome and adjusted for age and other potentially confounding factors. The relationship is inverse, graded and statistically significant. Although adjustment for potentially confounding factors somewhat attenuated the risk, this remained significant. Aerobics center longitudinal study (acls: n=>25,000 men.
