NUTRITN 580 Lecture Notes - Lecture 5: Hyoscyamine, Glipizide, Valsartan
15 Jan 2017
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Foods can affect drug therapy and drugs can affect food and nutritional status. Some interventions involve food components, whereas others involve specific nutrients. Enteral: uses gi tract or gut : orally or po tablets, capsules, liquids, rectally: suppositories used when upper gi tract is not functioning well. Drugs administered below the epidermis: intravenously (iv) Drugs administered into a blood vein: intramuscularly (im) Drugs administered into the muscle: sublingual (sl) Methotrexate, gentamicin, vancomycin, hydrocortisone: intradermally: ppd for tb between skin layers. Ppd=purified protein derivate skin test to diagnose silent (latent) tuberculosis (tb: topical. May work locally or may be absorbed and exert systematic effects: inhalation/nasal sprays. Polypharmacy: the risk of a food-drug interaction increases with the number of medications taken: polydrug use: when patients on > 5 drugs/day for a long time are especially high risk (especially elderly) Examples: metformin, glipizide, thyroxine, lipitor, diovan, fluoxetine.
