BIOLOGY 151 Lecture Notes - Lecture 20: Enzyme, Hexokinase, Dihydroxyacetone Phosphate
21 Dec 2015
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Bio151 lecture 20 substrates and enzymes. The first idea of substrates came from a lock and key, which says that the substrate acted as a key to the enzyme"s lock. Now the theory is induced fit, where the substrate moves in and changes the shape of the enzyme. There is usually one active site, but there are a few exceptions. Enzymes active site brings the reactants together. This active site holds the substrates it used to be called the lock and key mechanism. That is the active site would fit the substrate perfectly excluding other substrates. It"s now become clear that the active site often changes shape slightly when the substrate(s) enter(s) this changes the protein"s form slightly: induced fit. We"re back on form here this protein form is specificed for by the dna it is what evolves. They force substrates to be next to one another. The reactants are stable in a cell even if the reaction is exergonic.
