BIOLOGY 151 Lecture Notes - Lecture 13: Antennapedia, Ribosome, Nucleosome
21 Dec 2015
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Bio151 lecture 13 gene regulation and expression. Proteins have to get made in the right place at the right time. In this case a protein is made in the wrong place and the fly gets a leg instead of an antenna. Loss of function in regulatory region result in antennae for legs, gain of function lead to antenna for legs (antennapedia) Antennapedia is a hox gene a transcription factor. Humans, chimpanzees and bonobos share most of our genome. Depending on how you do the analysis 95%-99%. But we are very different (skeletal structure, bones). Controlling when genes are expressed and how much is critical to the organism. In a prokaryote things are somewhat simpler: transcription, translational, post translational. Q: rank the types of control in terms of speed of response (1 is fastest): a: 1 post-translational, 2 translational, 3 transcriptional. Q: what is an example of a post-translational modification: a: phosphorylation and ubiquitination. Chromatin remodeling does not happen in prokaryotes.
