BIOLOGY 151 Lecture Notes - Lecture 18: Tata-Binding Protein, Palindromic Sequence, Open Reading Frame
Document Summary
Activators: these proteins bind to genes at sites known as enhancers. Activators help determine which genes will be switched on, and they speed the rate of transcription. Repressors: these proteins bind to selected sets of genes at sites known as silencers. They interfere with the functioning of activators and this slow transcription. Coactivators: these adapter molecules integrate signals from activators and perhaps repressors and relay the results to basal factors. Basal transcription factors: in response to injunctions from activators, these factors position rna polymerase at the start of the protein-coding region of a gene and send the enzyme on its way. Promoter: sequences where rna polymerase binds to start transcription. Regulatory sequences: sequences where transcription factors bind that regulate the activity of rna polymerase and transcription. Tata box: sequence were tata binding protein binds to place form the initiation complex that includes rna polymerase 26bp upstream of the transcription start site.
