NURS 245 Lecture Notes - Lecture 15: Chronic Kidney Disease, Metabolic Acidosis, Kidney Failure
Document Summary
Renal impairment (40-60% normal gfr) looking at iltraion and absorpion. Filtraion decreases, s instead of iltering 180l/day, we may be iltering 90l/dy. So it"s lost even more of its funcion that iltraion has. Overall efect: even though we"re iltering less, we actually have polyuria (increased urine output), because we"re not reabsorbing. Renal insuiciency (10-40% normal gfr) overall, we are losing sodium and water, so: polyuria, dehydraion and weight loss, and hypotension/shock. Overall, we are also losing potassium (oten not reabsorbing it at the proximal tubules), so decreased excitability, skeletal muscle weakness, atrophy, paralysis, diiculty breathing, paralyic ileus, distenion, and cardiac arrhythmias. Renal failure (5-10% normal gfr) output is drasically decreased since so litle luid is geing iltered; now sodium and water ends up being retained. It leads to weight gain, venous distension, chf, systemic edema, and pulmonary edema. Overall, we start to retain k (luid isn"t geing iltered), leading to increased excitability, muscle cramping, colicky diarrhea, and arrhythmias.
