NURS 245 Lecture Notes - Lecture 10: Vascular Permeability, Extracellular Fluid, Liver Disease
Document Summary
Definitions of edema-changing of ratio of fluid in the plasma versus in the interstitium with more fluid going into the interstitium. (normal ratio of interstitial fluid to plasma is 80:20>ecf=33% of fluid/icf=66% of fluid) Increased diffusion distance-systemic edema=decreased oxygen delivery; pulmonary edema=inadequate exchanged of gases across alveoli. Increased pressure in closed cavity: cerebral edema-can cause pressure on the brain. Occlusion of lumens: laryngeal edema-causes throat to close becoming life threatening. Factors regulating fluid movement between plasma and interstitium. Net fluid movement = (hpc - hpi) - (copc - copi) Hpc: hydrostatic pressure capillary (p = n/v)-determinants-volume of blood (the more blood you have the higher the pressure will be) and contraction of blood (the harder the heart is contracting the higher the pressure will be). Specifically at capillary level-arteriolar resistance: how much fluid are you letting in and venous resistance: are you letting the fluid out.
