BIOLOGY 225 Lecture Notes - Lecture 5: Thyrotropin Receptor, Thyroid, Calcium Metabolism

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15 Jan 2017
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Thyroid gland: thyroid hormones act through nuclear receptors. Hypothalamus stimulates trh anterior pituitary tsh thyroid. More t3 & t4 less trh and tsh. Brain development differentiation - if there is less thyroid hormone, it will be associated w/ mental retardation; essential for. Hair growth in mammals: thyroid disorders. Goiter: low iodine in diet lowers thyroid hormone lowers negative feedback on brain and pituitary increases stimulation of thyroid gland: higher tsh levels, and lower t3/t4. Caused by present anti-bodies and act as tsh, which cause decreases in t3/t4. Agonist looks and acts like tsh stimulates t3/t4 higher levels of that. Grave"s disorder hyperthyroidism: body produces antibodies that attack tsh receptor. Higher rate of metabolism, bulging of eyes, weight. As calcium levels increase over normal levels, calcitonin increases, and contacts: Small intestine (inhibits calcium absorption from food) decrease in calcium levels: puts calcium from blood into bones bones get stronger.

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