BIOLOGY 173 Lecture Notes - Lecture 2: Reaction Rate
Document Summary
Concentration: in a simple chemical reaction (r p) Double reactants = double reaction rate: in an enzyme reaction. Rate depends on concentration of both enzyme and substrate. Rate is determined by whichever is limiting (usually enzyme) E + s es ep e + p. 2 components in a reaction: find component. Increase in substrate concentration = decrease in find time: process component. Es ep e + p. Vmax = maximum rate of reaction: at v max, all enzyme active sites are filled (saturated) Km = the substrate concentration at which the rate is half-maximal: km will vary with temperature, ph, also known as the affinity of the enzyme, low km is better than a high km. A molecule that has a similar shape to the substrate: can bind to the active site. Could produce a reaction with the unintended product: less effect of when substrate concentration is high.
