BIOLOGY 172 Lecture Notes - Lecture 10: Peripheral Membrane Protein, Integral Membrane Protein, Lipid Bilayer
Document Summary
Hydrophilic heads will find each other and water. Hydrophobic tails will find each other and shield themselves away from water. Phospholipids drift within one side of the lipid bilayer. Lipids move side to side more often than across to the other side of the bilayer. Fluidity and permeability is enhanced by unsaturated fatty acid tails (kinks make it more spacious) Viscosity (how much it sticks together) depends on temperature. Cholesterol (steroid) - hydrophobic & stabilizes a membrane (fills in the gaps) Sticks itself in between hydrocarbon tails, restricts their movement. Phospholipids are different on each side of the bilayer (length, saturation) Transporter proteins (channels move molecules across, carriers) Receptor sense something outside and relay a signal. Anchors can connect two cells together via membranes. Can be partially or entirely located within the membrane. Integral membrane protein - embeds itself fully into hydrophobic core - hydrophobic. Peripheral membrane protein - just associate with inside or outside - hydrophilic.
