BIOLCHEM 415 Lecture Notes - Lecture 17: Homeostasis, Phosphodiesterase, Adipose Tissue

• School: U of M
• Department: Biological Chemistry
• Course: BIOLCHEM 415
• Professor: Raymond Trievel

Document Summary

Three phases between different modes of energy generation. Once glucose reserves are exhausted within a few hours is the breakdown of glycogen. As soon at the diet glucose in the blood goes down, glycogen breakdown will already set in. The branching accomplishes two things: increase the solubility of the molecule, has more terminal residue. If you had a chain of glucose, you would only have one end where the reaction could occur. In glycogen, you have ends following the branching of the molecule and see that there are many ends. Glycogen metabolism is a stepwise release of glucose from many of the endpoints. The entry of glucose 1,6-phosphate releases glucose 6-phosphate. We have two majors sites of glycogen storage. One is the liver and the other is the muscle. Muscle has more of the glycogen (about 30% of our body mass is muscle and 2% of this is glycogen)