BIOLCHEM 415 Lecture 33: Lecture33_Chapter36_Apr4_Vojtek_2016

• School: U of M
• Department: Biological Chemistry
• Course: BIOLCHEM 415
• Professor: Mark Saper

Document Summary

The ow of gene+c informa+on from dna to protein. Transcription: the synthesis of rna from a dna template. Cellular rna is synthesized by rna polymerases synthesis of rna from a dna template catalyzed by rna polymerase. **the newly synthesized rna is complementary to the dna template. ** coding strand: the dna strand that has the same sequence as the rna product (with t instead of u) Ac+vated precursors in the form of ribonucleoside triphosphates. The 3"oh of the growing chain asacks the inner most phosphoryl ( ) group of the incoming ribonucleoside triphosphate: rna polymerase ini+ates and elongates the rna product, with the chain growing in the 5" to 3" direc+on. The rna transcript grows in a 5" to 3" direc+on. Is gtp or atp: no primer is necessary to begin rna synthesis, the rna transcript has a 5" triphosphate.