CHEM 312 Lecture Notes - Lecture 38: Bohr Radius, Nanomedicine, Nanometre
26 Apr 2019
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Proteins and nucleic acids: inorganic perspectives (plus remnants of nano) Electron-hole pair bohr radius ~1-10 nm. Unusual properties of metals on the nm scale. If you take gold and make particles ~10 nm in diameter, they become wine-red or blue-gray, depending on how close the particles are to each other. Mean free path of e- in metal: ~ 10-100 nm. G. mie (1908): light impinges upon the small conducting sphere . Down to ~4 nm for gold/silver, particles still large enough to support a conduction band; plasmon = coherent oscillation of conduction band electrons. Proteins are polymers made of amino acid monomers. Metal binding sites possible on side chains! Some amino acid side chains have acid-base character. Redox signaling in the cell: cysteine as a major participant! The peptide (or protein) sequence is read from n terminus to c terminus. The amide bond is planar and does not rotate (some double bond character)
