ANSC 452 Lecture Notes - Lecture 9: Myf6, Myocyte, Myogenin
15 Nov 2020
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Document Summary
Occurs with limb bod development by sclerotome (vertebrae) (paz1), myotome (muscle 1(pazus; dermatome (skin) myoblasts originate in the myotome of the somites. L y commitment/ detemination aprecursors become myoblasts migration myoblasts migrace to limb buds > can happen. 4 different. ation terminally differentiated & stop proliferating. 4 maturation/ hypertrophy x become muscle fibers & grow. nsize. & commitment marks musch lineage (w/ myod, my f5, mrf4, myogenin) Pax-3 stimulates six1 expression to express mrfs (muscle regulatory factors) Listops proliferation, promotes differentiation is my opt usually more in limb; my 15 rusually more. Ls growth factors will lead to growth arrest at g//sphase is commitment is encouraged by unt/shh from neurae tube & notocard h 3mp inhibits commitment. Sf escatter factory receptor myobedsos migrate towards scater factor. ~ proliferation going through all cycle : fgf/igf-1 helps proliferate. 4 myo statin/tnf- inhibits intrunk by c-met is a induced in progress zone.
