ADSC 4300 Lecture Notes - Lecture 7: Troponin, Organelle, Sarcomere
Document Summary
Muscle growth: is the same as muscle hypertrophy. After birth, many animals don"t get more myofibers. Hypertrophy vs hyperplasia: muscle fiber hyperplasia: usually occurs in a narrow window, during the first 2 thirds of prenatal development, muscle fiber hypertrophy: during last 3rd of gestation and . Longitudinal growth: related to stretch: sarcomere addition to end of myofibrils, the lenses of sarcomeres aren"t fixed, can increase more than 3x from birth to maturity. Imposed by bone lengthening during skeletal growth (stretched induced hypertrophy: mechanisms, protein synthesis & degradation, degradation: 3 system in muscle cells (also in all cells), lysosomal system. Lysosome is an organelle in a cell that"s wrapped by plasma membrane; it"s like a bag. Within the lysosome, thee is mixture of hydrolytic enzymes which can digest many things: called it trash bag , pathways to lysosomes: endocytosis, pathways to lysosomes: autophagy.