BSC 2010 Lecture Notes - Lecture 4: Nucleolus, Ion Channel, Cytoskeleton

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Cell theory- 1st unifying theory of biology: cells are the fundamental units of life, all organisms are composed of cells, all cells come from preexisting cells, implication of cell theory. Studying cell biology is the same as studying life. Volume of a cell- determines the amount of metabolic activity it carries out per unit time: as volume increases, surface area does not increase that much. The surface area of a cell- determine the number of substances that can enter or leave the cell: cells compensate by changing their shape to increase surface area. Ex: by being flat instead of spherical, or by having many. Cells can be studies structurally and chemically invaginations: two types of microscopes for visualizing cells. Light microscopes- use glass lenses and light. Electron microscopes- electromagnets focus an electron beam: chemical analysis. Involves breaking them open to make a cell-free extract. The composition and chemical reactions of the extract can be examined.

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