BSC 2010 Lecture Notes - Lecture 6: Covalent Bond, Homeostasis, Non-Competitive Inhibition
10 Sep 2013
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Document Summary
Concept 3. 3 some proteins act as enzymes to speed up biochemical reactions. Enzymes may use one or more mechanisms to catalyze a reaction: Inducing strain bonds in the substrate are stretched, putting it in an unstable transition state: are substrate orientation substrates are brought together so that bonds can form, r groups may be directly involved in the reaction. Maximum rate is used to calculate enzyme efficiency molecules of substrate converted to product per unit time (turnover). It ranges from 1 to 40 million molecules per second! Concept 3. 4 regulation of metabolism occurs by regulation of enzymes. Enzyme catalyzed reactions are part of metabolic pathways- the product of one reaction is a substrate for the next. Homeostasis- the maintenance of stable internal conditions. Cells can regulate metabolism by controlling the amount of an enzyme. Cells often have the ability to turn synthesis of enzymes off or on. Chemical inhibitors can bind to enzymes and slow reaction rates.
