BSC 2010 Lecture Notes - Lecture 8: Abo Blood Group System, Thomas Hunt Morgan, Mendelian Inheritance

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One gene may have more than two alleles. Multiple alleles increase the number of possible phenotypes and may show a hierarchy of dominance in heterozygotes. Figure 8. 9 multiple alleles for coat color in rabbits. Some alleles are neither dominant nor recessive, and heterozygotes have an intermediate phenotype. Figure 8. (cid:1005)(cid:1004) i(cid:374)(cid:272)o(cid:373)plete do(cid:373)i(cid:374)a(cid:374)(cid:272)e follo(cid:449)s me(cid:374)del"s la(cid:449)s. Two alleles of a gene produce both phenotypes in the heterozygote. Abo blood group system has three alleles of the gene: ia, ib, and io. Figure 8. 11 abo blood groups are important in transfusions. Phenotypic expression of one gene is influenced by another gene. Allele b (black) is dominant to b (brown) Allele e (pigment deposition) is dominant to e (no pigment deposition hair is yellow) Gene e determines the phenotypic expression of gene b. Genotype and environment often interact to determine phenotype. These rabbits and cats have a mutant allele for the coat color gene.

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