NTDT401 Lecture Notes - Lecture 7: Nicotinamide, Isoniazid, Malate Dehydrogenase
Document Summary
3 dehydrogenases in tca cycle based on nad. *nad, nadp not absorbable; have to reverse that into the preform to absorb them. **names, food sources, functions, deficiencies etc exams summarize vitamins nicotinic acid treat hyperlipidemia to reduce cholesterol nicotinamide coenzyme form of niacin. Ribose & adenosine added to nicotinamide after digestion and removed before absorption. *foods high in proteins, whole & enriched grains, dairy. **corn is not a good source low in tryptophan. 2nd layer bran (rough skin, edible, rich in nutrients) 3rd layer endosperm (rich in cho and proteins) Germ (rich in nutrients where new life grows if planted) *by removing bran unenriched white bread; doesn"t get as many nutrients. *enriched white bread only top nutrients (thiamin, riboflavin, folate, niacin, iron); almost at 90% regular level. *any time flour is processed, top 5 nutrients must be added (enriched) 60 mg trp= 1 mg niacin= 1 niacin equivalent. *pathway happens in liver and is b6 dependent (slide 10)