NTDT401 Lecture Notes - Lecture 25: Electrochemical Gradient, Extracellular Fluid, Kidney
8 Dec 2016
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Na gradient from na/k atpase pump the electrochemical gradient is created by Atp pumps 3 na+ ions for 2 k+ ionsthis maintains the membrane potential! 3 basic pathways of absorption**: na/glucose co-transport, na+/h+ & cl/hco3 exchange, electrogenic na+ absorption main absorption routes are, na/glucose co-transport, na+/h+ & cl/hco3 exchange. Carrier cotransports na w/ glucose into cell. Once in cell, na/k atpase works to pump na+ across membrane --> glucose exits through membrane by facilitated diffusion. Sodium = pumped basolaterally / cl = diffuses passively electrogenic na+ absorption. Functions*** (list: extracellular fluid compartment (efc) volume. Result of excess fluid loss (diarrhea, vomiting, sweating etc. ) Lethargy --> coma --> death biochemical indices. Hematocrit (high) food sources high in sodium. Mac & cheese, chips, canned foods, corn dog, etc. food sources high in sodium - na/k levels increased na, decreased k food sources low in sodium.
