BISC300 Lecture Notes - Lecture 2: Isopropyl Alcohol, Disinfectant, Bactericide
27 Nov 2016
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Document Summary
Control of microorganisms in the environment: how to control microbial growth. Use of chemical to kill or inhibit growth of microorganisms within host tissue: agents that kill microorganisms or inhibit their growth. The pattern of microbial death: microorganisms are not killed instantly, population death usually occurs exponentially, measure of agent"s killing efficiency. Decimal reduction time (d value)-time to kill 90% Z value is the temperature changes to reduced d value by 1 log. At temp, takes time to reduce a log of bacteria. Conditions influencing the effectiveness of antimicrobial agent activity: population size larger populations take longer to kill than smaller populations, population composition. Microorganisms differ markedly in their sensitivity to antimicrobial agents. Commonly used as laboratory and hospital disinfectants. Act by denaturing proteins and disrupting cell membranes. Disagreeable odor and can cause skin irritation tuberculocidal, effective in presence of organic material, and long lasting. Among the most widely used disinfectants and antiseptics. 2 most common are ethanol and isopropanol.
