BISC207 Lecture Notes - Lecture 2: C-Terminus, N-Terminus, Carboxylic Acid

• School: University of Delaware
• Department: Biological Sciences
• Course: BISC207
• Professor: Jennifer Nauen

Document Summary

Proteins consist of 1 or more polypeptides. The building block, or monomer, is the amino acid. Amino acid structure (figure 3. 1a) (aa = amino acid) Loss of the proton is energetically favorable. Group aa by side chain chemistry (figure 3. 2) Use en to determine the polarity of aa side chains. Answer = c. nonpolar bc there is not a big enough en between c and h. There are 20 typical amino acids - figure 3. 2. Peptide - a linear chain covalently linked amino acids. More than 50, you call it a polypeptide. (amino terminus) n -terminus to (carboxyl terminus) c- terminus. Link amino acids; a dehydration reaction forms a peptide bond and water (figure. The carboxyl group of one interacts with the amino group of another. Peptide bonds are single covalent bonds, but partial sharing of a 2nd electron pair makes the bond rigid (figure 3. 5) C = 0 is a carboxyl group; n-h is an amide group (figure 3. 7)