BISC207 Lecture Notes - Lecture 13: Francis Crick, Messenger Rna, Start Codon
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BISC207 Full Course Notes
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Direction of synthesis for rna is 5" 3". Carries instructions for polypeptide synthesis from nucleus to ribosomes in the cytoplasm. Contains 2 functional sites: one called anticodon site recognizes a codon and the other has the appropriate amino acid attached to it. Carries amino acids to the ribosome and matches them to the coded mrna message. Located in the cytoplasm of a cell, where ribosomes are found. rrna directs the translation of mrna into proteins. Forms an important part of both subunits of the ribosome. Dna is transcribed into an mrna, which is then translated into a protein. Exception: following retrovirus infection, reverse transcriptase converts viral rna into proviral dna, which is then incorporated into the dna of the host cell in the nucleus (hiv does this) The process of assembling a polypeptide based on the nucleotide sequence of mrna is called translation. Francis crick proposed that the sequence of bases in dna acted as a code.