ANFS332 Lecture Notes - Lecture 14: Orthomyxoviridae, Dna Virus, Herpesviridae
4 Feb 2020
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Document Summary
Term was first used in the context of an infectious disease in 1728. May be defined as acellular organisms whose genomes consist of nucleic acid and which obligately replicate inside host cells. Use host metabolic machinery and ribosomes to form a pool of components which assemble into particles called virions, which serve to protect the genome and to transfer it to other cells. But they do reproduce and may adapt to new hosts. Inert carriers of the viral genome and are assembled inside of host cells from virus-specific components. Do not grow and do not form by division. Helical nucleocapsids are simple, isometric nucleocapsids are more complex. All isometric virions are constructed around a basic icosahedron, a solid. Lipid bilayer membranes with viral proteins inserted. Usually an inner layer (matrix) in contact with the nucleocapsid. Rna or dna, ss or ds, single or multiple components. This includes all classes of cellular organisms plant, animal (vert/invert), bacteria, archaea, protozoa, fungi.
