ANFS251 Lecture Notes - Lecture 5: Blastomycosis, Sepsis, Tetracycline Antibiotics
12 Sep 2017
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Document Summary
Ixodes scapularis (deer ick or black legged tick, only three species carry the disease organism) In humans symptoms appear 3-30 days after the tick bite. Fatigue: chills and fever, headache, muscle and joint pain. Swollen lymph nodes: bull"s eye circular skin rash, erythema migrans. Some symptoms may not appear until weeks after a tick bite. Borrelia burgdorferi: borrelia burgdorferi is a spirochete. Spirochetes are a group of bacteria that have a unique mode of motility by means of axial filaments (endoflagella: the spirochetes have a unique cell surface which accompanies their unique type or motility. For pathogens, this allows the spirochetes to hide their flagella, which are normally antigenic, from the host immune disease: the spirochetes are not classifies as either gram-positive or gram negative. Therefore, it has a gram-negative bacterial type cell wall, despite its staining characteristics: the outer membrane of borrelia burgdorferi is composed of various unique outer surface proteins (osp) that have been characterized.
