ANFS 345 Lecture 8: 10/11/18

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Pathways of neuronal ap > muscle contraction and calcium release > sarcomere contraction. Process of pressure driven bulk flow of blood to all parts of the body. Atria work as one unit and ventricles work as separate unit. Forms the annuli fibrosi ( fibrous rings ) which hold heart valves. Located between the atria and the ventricles. Blood returns to heart via pulmonary veins. Blood returns to heart via superior/inferior venae cavae. Blood passes in 1 direction via interconnected system, moving oxygenated blood to tissues, then returning deoxygenated blood to right heart & lungs. Cardiac muscle cells (myocardium) connected by gap junctions called intercalated discs. Once stimulus received, it flows from cell to cell so that all contract together (functional syncytium). Since myocardium of the atria and ventricles is separated by fibrous skeleton, each must be stimulated separately. Cardiac muscle cells have a resting potential of -90mv.

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