BIMM 120 Lecture Notes - Lecture 1: Linezolid, Human Microbiota, Genetic Drift
26 Oct 2018
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Document Summary
What is microbiology: greek: micro = small, bios = life, studies microorganisms, which are organisms that cannot be seen clearly by the naked eye. Generally, 1 mm or less in diameter, often unicellular, and lack differentiated tissues if multicellular: ex: bacteria, archaea, protozoa, algae, fungi, viruses, and prions. Black death: bubonic plague wiped out 1/3 of european population twice: caused by bacteria, not a good representative of microbes. Evolution: change in allele frequencies in a population over time: occurs quickly in prokaryotes. You step on green bugs, causes shift: bottleneck: there is a drastic reduction in population. The remaining organisms that survive make up the new gene pool fou(cid:374)der effe(cid:272)t: (cid:374)e(cid:449)l(cid:455) fou(cid:374)ded populatio(cid:374)s (cid:894)fro(cid:373) (cid:373)igratio(cid:374), for e(cid:454)a(cid:373)ple(cid:895) do(cid:374)(cid:859)t always represent the genetic diversity in their sources. 2 case studies: mrsa: methicillin-resistant staphylococcus aureus. Used as solidifying agent for culture media, generally not metabolized by microbes.
