PSYC 2501 Lecture Notes - Lecture 17: Perirhinal Cortex, Synapse, Memory Consolidation
26 Apr 2018
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Memory & the brain (7)
Thursday, March 22, 2018
12:33 PM
• Memory and the brain
• Microlevel
• The neuron/synapse (synaptic consolidation)
• Learning and memory are represented in the brain by physiological
changes at the synapse
• Synaptic changes due to learning
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• Presynaptic (sending neuron)
• Postsynaptic (receiving neuron)
• The structural changes at the synapse in both the pre- and postsynaptic
neurons lead to greater transmitter release and absorption and an increase in
firing of postsynaptic neuron (enhanced responding)
• Long term potentiation
• Long-lasting enhancement in signal transmission between two neurons
that results from stimulating them synchronously
• The change in the structure and strength of the synapse is a neural
record of an experience (a memory)
• Macrolevel
• The brain/neural circuits (systems consolidation)
• Memory is represented by changes at the synapse and also changes in
the brain
• Some areas of the brain involved in memory
• Medial temporal lobe (MTL)
• Includes the hippocampus, perirhinal cortex, parrahippocampal
cortex, and entorhinal cortex
• Amygdala
• Memory and brain
• Exposure to a stimulus
• Hippocampus reactivates later on
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