PNB 2265 Lecture Notes - Lecture 28: Brush Border, Creatinine, Active Transport
10 Apr 2017
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Urinary bladder: bladder wall, detrusor muscle, smooth muscle of bladder, can stretch to hold more, transitional epithelium, layered epithelium subtype that is able to withstand stretch, by changing cell"s shape. Internal and external urethral sphincters: internal = involuntary smooth muscle, eternal = skeletal muscle fibers, controlled by somatic nervous system, want to control this so you can hold your pee, relax the sphincter to open it. Micturition reflex: reflex mediated by parasympathetic nervous system, voluntary control through descending input form higher centers. If present, would favor filtration: fluid pressure in bowman"s space (cid:523)pbs(cid:524)=hydrostatic pressure of fluid in bowman"s, blood colloid osmotic pressure ( gc(cid:524): osmotic force due to protein in plasma, nfp=pgc-pbs- gc, example=60-15-29=16 mmhg, to calculate net glomerular filtration pressure. If we dilate the afferent arteriole, then __________: pgc will increase, pgc will decrease, pbs will decrease, nfp will increase, nfp will decrease, both a and d.
