PNB 2265 Lecture Notes - Lecture 10: Vagus Nerve, Stroke Volume, Cardiac Output

• School: UConn
• Department: Physiology and Neurobiology
• Course: PNB 2265
• Professor: Kristen Kimball

Document Summary

After late ventricular systole: closing valves. Heart rate (beats/min: ~6l per min. Variations in heart rate and stroke volume change cardiac output. Pace maker are innervated autonomic and are adrenergic hormones: epi and norepi can change, innervated by sympathetic and parasympathetic. Release epi onto pace maker cells: cardioacceleratory center, ne, can control both stroke volume and heart rate speed. Parasympathetic: vagus nerve, cardioinhibitory center, ach. Constantly released to slow down ap: decrease camp and decrease pace, if you block parasympathetic: increase in basal heart rate in a person, not good at changing stroke volume, only heart rate. The vagus nerve decreases heart rate by decreasing the rate of sa node filling. Beta receptors on heart to respond to epi and norepi*** In the heart, ne/e bind beta adrenergic receptors g-protein coupled receptors (gs) Arteries: carry blood away from heart distribution. Veins: carry blood toward the heart collection.